1. Peyton Manning vs. Detroit Lions
O-13 goes to 0-14 after this one. The winless Lions are heading to Indianapolis at a time when the Colts are on a roll and after Sunday's 35-3 blowout over the Cincinnati Bengals, Peyton showed that even in blowouts he'll get his numbers: 277 yards and 3 TDs. Look for similar numbers this Sunday and Peyton is the top fantasy QB of the week.
2. Kurt Warner vs. Minnesota Vikings
Even though the Arizona Cardinals clinched the NFC West on Sunday, it's still too early to begin resting players before the NFL playoffs begin. And with the Cards' inability to generate much from the ground game in general, look for Warner to continue his air assault on the Vikings and reach the 300-yard mark with a few scores.
3. Tony Romo vs. New York Giants
Romo has historically been a Giants killer throughout his career. And in this Sunday Night match-up, the Cowboys will be playing on pure desperation. Look for Romo to have a solid game as his line will provide him time to locate his prime targets, and for Romo to finish with at least two TDs.
4. Eli Manning vs. Dallas Cowboys
The other signal caller in the game, Eli Manning, also has a history of playing well against the Cowboys and in particular in Dallas. The Giants will look to erase Sunday's loss to the Eagles from their memory and look for Eli to have a big game spreading the ball around to his playmakers and putting a few into the end zone.
1. Jeff Garcia vs. Atlanta Falcons
The Falcons have played pretty solid defense throughout the season and have clamped down on most opposing teams' running games, so look for Garcia to have some opportunities in the passing game and for him to locate Bryant and Galloway on at least one deep pass.
2. Matt Schaub vs. Tennessee Titans
The Titans bring a dominant defense into this football game but division rivalries have been known to produce uncharacteristic outcomes. Schaub has a solid group of playmakers at his disposal and after today’s 400+ yard game, look for at least 250 this weekend.
Others with Favorable Match-ups:
1. Donovan McNabb vs. Cleveland Browns
McNabb will try and keep the Eagles' playoff hopes alive and the Browns are ready for '09. Look for McNabb to once again enjoy a solid performance on Monday night.
2. Jake Delhomme vs. Denver Broncos
Delhomme has had his ups and downs this season, but against the Broncos, he should have his opportunities. The Broncos have had trouble all season getting pressure on opposing QBs, and Delhomme has the weapons to make them pay.
The Jaguars have mailed in 2008 and the Green Bay Packers are close to doing so as well. Sitting two games back with three to play, the Packers must win out and get help. Look for Rodgers to play his part and for the passing game to come up big on Sunday.