Single Season Home Runs
| Rank | Player | HR | Season |
|---|---|---|---|
| 1 | Barry Bonds | 73 | 2001 |
| 2 | Mark McGwire | 70 | 1998 |
| 3 | Sammy Sosa | 66 | 1998 |
| 4 | Mark McGwire | 65 | 1999 |
| 5 | Sammy Sosa | 64 | 2001 |
| 6 | Sammy Sosa | 63 | 1999 |
| 7 | Roger Maris | 61 | 1961 |
| 8 | Babe Ruth | 60 | 1927 |
| 9 | Babe Ruth | 59 | 1920 |
| 10 (tie) | Jimmie Foxx | 58 | 1932 |
| 10 (tie) | Hank Greenberg | 58 | 1938 |
| 10 (tie) | Mark McGwire | 58 | 1997 |
| 10 (tie) | Ryan Howard | 58 | 2006 |
