List of players with the most doubles during the 1906 baseball season
| Rank | Player Name | Total 2Bs |
| 1 | Nap Lajoie | 48 |
| 2 | Harry Davis | 42 |
| 3 | Honus Wagner | 38 |
| 4 | Sherry Magee | 36 |
| 5 | Elmer Flick | 34 |
| 6 | Danny Murphy | 28 |
| 6 | Kitty Bransfield | 28 |
| 8 | Harry Steinfeldt | 27 |
| 8 | Jimmy Sheckard | 27 |
| 8 | Terry Turner | 27 |
| 11 | George Davis | 26 |
| 12 | Charlie Hickman | 25 |
| 12 | George Stone | 25 |
| 12 | Hobe Ferris | 25 |
| 12 | Jimmy Williams | 25 |
| 12 | John Anderson | 25 |
| 12 | Sam Crawford | 25 |
| 18 | Chick Stahl | 24 |
| 18 | Frank Chance | 24 |
| 20 | Art Devlin | 23 |
| 20 | Frank LaPorte | 23 |
| 20 | Hal Chase | 23 |
| 20 | Harry Lumley | 23 |
| 20 | Monte Cross | 23 |
| 20 | Socks Seybold | 23 |
