List of pitchers with the most runs allowed during the 1906 baseball season
| Rank | Player Name | Total Rs |
| 1 | Gus Dorner | 157 |
| 1 | Irv Young | 157 |
| 3 | Gus Dorner | 152 |
| 4 | George Mullin | 139 |
| 5 | Big Jeff Pfeffer | 138 |
| 5 | Jack Chesbro | 138 |
| 7 | Cy Young | 137 |
| 8 | Cy Falkenberg | 136 |
| 9 | Vive Lindaman | 132 |
| 10 | Joe Harris | 130 |
| 11 | Doc Scanlan | 128 |
| 11 | Elmer Stricklett | 128 |
| 11 | Johnny Lush | 128 |
| 14 | Joe McGinnity | 127 |
| 15 | Harry McIntire | 123 |
| 16 | George Winter | 118 |
| 16 | Tom Hughes | 118 |
| 18 | Al Orth | 115 |
| 19 | Frank Owen | 114 |
| 20 | Charlie Smith | 113 |
| 21 | Jim Pastorius | 111 |
| 22 | Mal Eason | 109 |
| 23 | Casey Patten | 106 |
| 24 | Bob Wicker | 105 |
| 24 | Jake Weimer | 105 |
