List of pitchers with the most games started during the 1906 baseball season
| Rank | Player Name | Total GSs |
| 1 | Jack Chesbro | 42 |
| 2 | Irv Young | 41 |
| 3 | George Mullin | 40 |
| 4 | Al Orth | 39 |
| 4 | Jake Weimer | 39 |
| 6 | Joe McGinnity | 37 |
| 6 | Tully Sparks | 37 |
| 8 | Big Jeff Pfeffer | 36 |
| 8 | Cy Falkenberg | 36 |
| 8 | Frank Owen | 36 |
| 8 | Otto Hess | 36 |
| 8 | Vic Willis | 36 |
| 8 | Vive Lindaman | 36 |
| 14 | Christy Mathewson | 35 |
| 14 | Elmer Stricklett | 35 |
| 14 | Johnny Lush | 35 |
| 17 | Bob Rhoads | 34 |
| 17 | Cy Young | 34 |
| 17 | Rube Waddell | 34 |
| 20 | Doc Scanlan | 33 |
| 20 | Gus Dorner | 33 |
| 20 | Harry Howell | 33 |
| 20 | Jack Taylor | 33 |
| 24 | Bob Ewing | 32 |
| 24 | Casey Patten | 32 |
