List of Cleveland Indians pitchers with the most saves
| Rank | Player Name | SVs |
| 1 | Bob Wickman | 139 |
| 2 | Doug Jones | 129 |
| 3 | Jose Mesa | 104 |
| 4 | Michael Jackson | 94 |
| 5 | Ray Narleski | 53 |
| 6 | Steve Olin | 48 |
| 7 | Jim Kern | 46 |
| 7 | Sid Monge | 46 |
| 9 | Gary Bell | 45 |
| 10 | Ernie Camacho | 44 |
| 11 | Dave LaRoche | 42 |
| 12 | Dan Spillner | 41 |
| 13 | Joe Heving | 32 |
| 13 | Don Mossi | 32 |
| 15 | Willis Hudlin | 31 |
| 15 | Danys Baez | 31 |
| 17 | Ed Klieman | 30 |
| 18 | Don McMahon | 28 |
| 19 | Jim Bagby | 26 |
| 19 | Eric Plunk | 26 |
| 21 | Tom Buskey | 25 |
| 22 | Ted Abernathy | 23 |
| 22 | Mel Harder | 23 |
| 24 | Bob Lemon | 22 |
| 24 | Stan Williams | 22 |
