List of Chicago Cubs pitchers with the most saves
| Rank | Player Name | SVs |
| 1 | Lee Smith | 180 |
| 2 | Bruce Sutter | 133 |
| 3 | Randy Myers | 112 |
| 4 | Don Elston | 63 |
| 5 | Phil Regan | 60 |
| 6 | Ryan Dempster | 59 |
| 7 | Rod Beck | 58 |
| 8 | Mitch Williams | 52 |
| 9 | Joe Borowski | 44 |
| 10 | Charlie Root | 40 |
| 11 | Lindy McDaniel | 39 |
| 11 | Ted Abernathy | 39 |
| 11 | Mordecai Brown | 39 |
| 14 | Rick Aguilera | 37 |
| 14 | Terry Adams | 37 |
| 16 | Paul Assenmacher | 33 |
| 17 | LaTroy Hawkins | 29 |
| 17 | Jack Aker | 29 |
| 19 | Dutch Leonard | 28 |
| 19 | Turk Lown | 28 |
| 21 | Guy Bush | 27 |
| 21 | Tom Gordon | 27 |
| 23 | Dick Tidrow | 25 |
| 24 | Darold Knowles | 24 |
| 25 | Oscar Zamora | 23 |
