List of Boston Red Sox pitchers with the most games
| Rank | Player Name | Gs |
| 1 | Bob Stanley | 637 |
| 2 | Tim Wakefield | 443 |
| 3 | Derek Lowe | 384 |
| 4 | Roger Clemens | 383 |
| 5 | Ellis Kinder | 365 |
| 6 | Cy Young | 327 |
| 7 | Ike Delock | 322 |
| 8 | Bill Lee | 321 |
| 9 | Mike Timlin | 297 |
| 10 | Mel Parnell | 289 |
| 11 | Greg Harris | 287 |
| 12 | Mike Fornieles | 286 |
| 12 | Dick Radatz | 286 |
| 14 | Luis Tiant | 274 |
| 15 | Rich Garces | 261 |
| 16 | Sparky Lyle | 260 |
| 17 | Joe Dobson | 259 |
| 18 | Jack Wilson | 258 |
| 19 | Bill Monbouquette | 254 |
| 20 | Frank Sullivan | 252 |
| 21 | Jack Russell | 242 |
| 22 | Tom Brewer | 241 |
| 22 | Dennis Eckersley | 241 |
| 24 | Tony Fossas | 239 |
| 25 | Bruce Hurst | 237 |
