List of Baltimore Orioles pitching with the lowest earned run average
| Rank | Player Name | ERA |
| 1 | Harry Howell | 2.064 |
| 2 | Rube Waddell | 2.190 |
| 3 | Stu Miller | 2.370 |
| 4 | Hoyt Wilhelm | 2.428 |
| 5 | Fred Glade | 2.520 |
| 6 | Barney Pelty | 2.620 |
| 7 | Jack Powell | 2.630 |
| 8 | Carl Weilman | 2.671 |
| 9 | Eddie Watt | 2.746 |
| 10 | Pat Dobson | 2.781 |
| 11 | Jim Palmer | 2.858 |
| 12 | Billy O'Dell | 2.864 |
| 13 | Joe Lake | 2.886 |
| 14 | Dick Hall | 2.898 |
| 15 | Willie Sudhoff | 2.922 |
| 16 | Jim Hardin | 2.956 |
| 17 | Earl Hamilton | 2.983 |
| 18 | Allen Sothoron | 2.986 |
| 19 | Nels Potter | 3.050 |
| 20 | Tom Phoebus | 3.066 |
| 21 | Bill Bailey | 3.083 |
| 22 | Robin Roberts | 3.089 |
| 23 | Steve Barber | 3.129 |
| 24 | Dave Davenport | 3.163 |
| 25 | Mike Cuellar | 3.180 |
