List of Arizona Diamondbacks players with the most strikeouts
| Rank | Player Name | SOs |
| 1 | Luis Gonzalez | 580 |
| 2 | Steve Finley | 467 |
| 3 | Jay Bell | 437 |
| 4 | Matt Williams | 383 |
| 5 | Damian Miller | 363 |
| 6 | Tony Womack | 303 |
| 7 | Craig Counsell | 294 |
| 8 | David Dellucci | 288 |
| 9 | Chad Tracy | 267 |
| 10 | Kelly Stinnett | 245 |
| 11 | Junior Spivey | 242 |
| 12 | Travis Lee | 219 |
| 13 | Randy Johnson | 213 |
| 14 | Danny Bautista | 198 |
| 15 | Erubiel Durazo | 195 |
| 16 | Andy Fox | 174 |
| 17 | Quinton McCracken | 160 |
| 18 | Shawn Green | 159 |
| 19 | Chris Snyder | 151 |
| 20 | Troy Glaus | 145 |
| 21 | Alex Cintron | 138 |
| 22 | Tony Clark | 128 |
| 23 | Reggie Sanders | 126 |
| 24 | Brandon Webb | 120 |
| 25 | Luis Terrero | 119 |
