List of Arizona Diamondbacks pitchers with the most earned runs allowed
| Rank | Player Name | ERs |
| 1 | Brian Anderson | 422 |
| 2 | Randy Johnson | 409 |
| 3 | Miguel Batista | 321 |
| 4 | Brandon Webb | 311 |
| 5 | Curt Schilling | 273 |
| 6 | Omar Daal | 216 |
| 7 | Armando Reynoso | 214 |
| 8 | Andy Benes | 208 |
| 9 | Claudio Vargas | 154 |
| 10 | Elmer Dessens | 144 |
| 11 | Byung-Hyun Kim | 117 |
| 12 | Todd Stottlemyre | 115 |
| 13 | Russ Ortiz | 107 |
| 14 | Javier Vazquez | 106 |
| 15 | Casey Fossum | 105 |
| 16 | Mike Koplove | 104 |
| 17 | Greg Swindell | 95 |
| 18 | Mike Morgan | 93 |
| 19 | Rick Helling | 88 |
| 20 | Willie Blair | 87 |
| 21 | Lance Cormier | 86 |
| 22 | Edgar Gonzalez | 82 |
| 22 | Brad Halsey | 82 |
| 24 | Steve Sparks | 81 |
| 25 | Matt Mantei | 78 |
